Site rseA
- Name: rseA
- Type: Gene
- Synonyms
b2572 MG1655 locus tag mclA genbank partial sequence ECU10148 yfiJ - Mnemonic: regulation of sigma E
- Left End Point: 58.35
- Right End Point: 58.36
- Products:
membrane protein regulator (inhibitor) of sigma E transcriptional activity stress signal transducer for protein misfolding in envelope anti-Sigma E factor - Direction: <
- Properties:
Property Comment encodes membrane protein NULL regulatory gene NULL - Priority: 0
- 1 Alleles of This Gene
rseA741(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG12341 EcoliWiki rseA - Comment:
- originally, A.De Las Penas, L.Connally, and C.Gross, personal communication. also, Raina and Missiakis, unpub. direct negative regulator of sigma-E (protein misfolding path in envelope)
- References:
- De Las Penas, A., L. Connolly, C.A. Gross 1997. The sigmaE-mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE. Mol.Microbiol. 24:373-385
- Missiakas, D., M.P. Mayer, M. Lemaire, C. Georgopoulos, S. Raina 1997. Modulation of the Escherichia coli sigmaE (RpoE) heat-shock transcription-factor activity by the RseA, RseB and RseC proteins. Mol.Microbiol. 24:355-371
- Alba, B.M., J.A. Leeds, C. Onufryk, C.Z. Lu, C.A. Gross 2002. DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response. Genes Dev. 16:2156-2168