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Site dgt(promoter)
- Name: dgt(promoter)
- Type: Regulatory Site
- Synonyms
dgtH optA - Mnemonic: dGTPase
- Left End Point: 3.85
- Right End Point: 3.85
- Products:
deoxyguanosine 5'-triphosphate triphosphohydrolase dGTPase - Direction: <
- Priority: 1
- Comment:
- Selectable phenotype. Failure to support growth of phage T7 gene 1.2 mutants.
- References:
- Saito, H., C.C. Richardson 1981. Genetic analysis of gene 1.2 of bacteriophage T7: isolation of a mutant of Escherichia coli unable to suppoort the growth of T7 gene 1.2 mutants. J.Virology 37:343-351
- Myers, J.A. 1987. Gene 1.2 protein of bacteriophage T7. Effect on deoxyribonucleotide pools. J.Biol.Chem. 262:5288-5292
- Beauchamp, B.B., C.C. Richardson 1988. A unique deoxyguanosine triphosphatase is responsible for the OptA1 phenotype of Escherichia coli. Proc.Natl.Acad.Sci.USA 85:2563-2567
- Seto, D, SK Bhatnagar, MJ Bessman 1988. The purification and properties of deoxyguanosine triphosphate triphosphohydrolase from Escherichia coli. J. Biol. Chem. 263(3):1494-9.
- Quirk, S., D. Seto, S.K. Bhatnagar, P. Gauss, L. Gold, M.J. Bessman 1989. Location and molecular cloning of the structural gene for the deoxyguanosine triphosphate triphosphohydrolase of Escherichia coli. Mol.Microbiol. 3:1391-1395