Site gnsA
- Name: gnsA
- Type: Gene
- Synonyms
b4517 MG1655 locus tag sfa Rock et al. for suppressor of fabA6 yccL - Mnemonic: secG Null Suppressor
- Left End Point: 22.66
- Right End Point: 22.66
- Direction: >
- Priority: 0
- 1 Alleles of This Gene
gnsA735(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG13233 EcoliWiki gnsA - Comment:
- suppressor of fabA6(ts) and secG null (Cs). Increases acidic phospholipids by inhibiting phosphatidylethanolamine synthesis (at low temperatures). See PT# 96337 and 96338 for LEP,REP ecogene
- References:
- Rock, C.O., J.T. Tsay, R. Heath, S. Jackowski 1996. Increased unsaturated fatty acid production associated with a suppressor of the fabA6(Ts) mutation in Escherichia coli. J.Bacteriol. 178:5382-5387
- Sugai, R, H Shimizu, K Nishiyama, H Tokuda 2001. Overexpression of yccL (gnsA) and ydfY (gnsB) increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation of Escherichia coli. J. Bacteriol. 183(19):5523-8.
- Sugai, R., H. Shimizu, K. Nishiyama, H. Tokuda 2004. Overexpression of gnsA, a multicopy suppressor of the secG null mutation, increases acidic phospholipid contents by inhibiting phosphatidylethanolamine synthesis at low temperatures. J.Bacteriol. 186