Site groL
- Name: groL
- Type: Gene
- Synonyms
b4143 MG1655 locus tag groEL mopA 90 map - Mnemonic: growth of phage
- Left End Point: 94.17
- Right End Point: 94.20
- Products:
GroEL Hsp60 chaperone subunit - Direction: >
- Properties:
Property Comment encodes chaperone molecule NULL heat shock regulon NULL - Priority: 1
- 1 Alleles of This Gene
groL768(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10599 EcoliWiki groL - Comment:
- Selectable phenotype. Phage LAM + phage 434, phage T4 resistance.
- References:
- Georgopoulos, C., R.W. Hendrix, C. Kaiser 1972. Role of the host cell in bacteriophage morphogenesis: effects of a bacterial mutation on T4 head assembly. Nature New Biol. 239:38-41
- Neidhardt, F.C., T.A. Phillips, R.A. VanBogelen, M. W. Smith, Y. Georgalis, A.R. Subramanian 1981. Identity of the B56.5 protein, the A-protein, and the groE gene product of Escherichia coli. J.Bacteriol. 145:513-520
- Tilly, K., H. Murialdo, C. Georgopoulos 1981. Identification of a second Escherichia coli groE gene whose product is necessary for bacteriophage morphogenesis. Proc.Natl.Acad.Sci.USA 78:1629-1633
- Lecker, S., R. Lill, T. Ziegelhoffer, C. Georgopoulos, P.J. Bassford, C.A. Kumamoto, W. Wickner 1989. Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro. EMBO J. 8:
- Fayet, O., T. Ziegelhoffer, C. Georgopoulos 1989. The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures. J.Bacteriol. 171:1379-1385
- Georgopoulos, C, D Ang 1990. The Escherichia coli groE chaperonins. Semin. Cell Biol. 1(1):19-25.
- Donnelly, C.E., G.C. Walker 1992. Coexpression of UmuD' with UmuC suppresses the UV mutagenesis deficiency of groE mutants. J.Bacteriol. 174:3133-3139
- Laine, P.S., R.R. Meyer 1992. Interaction of the heat shock protein GroEL of Escherichia coli with single-stranded DNA-binding protein: suppression of ssb-113 by groEL46. J.Bacteriol. 174:3204-3211
- Burnett, BP, AL Horwich, KB Low 1994. A carboxy-terminal deletion impairs the assembly of GroEL and confers a pleiotropic phenotype in Escherichia coli K-12. J. Bacteriol. 176(22):6980-5.
- Kandror, O., M. Sherman, M. Rhode, A.L. Goldberg 1995. Trigger factor is involved in GroEL-dependent protein degradation in Escherichia coli and promotes binding of GroEL to unfolded proteins. EMBO J. 14:6021-6027
- Bulatnikov, I.G., O.V. Polyakova, R.A. Asryants, N.K. Nagradova, V.I. Muronetz 1999. Participation of chaperonin GroEL in the folding of D-glyceraldehyde-3-phosphate dehydrogenase.An approach based on the use of different oligomeric forms of the enzyme
- Tieman, B.C., M.F. Johnston, M.T. Fisher 2001. A comparison the GroE chaperonin requirements for sequentially and structurally homologous malate dehydrogenases: the importance folding kinetics and solution environment. J.Biol.Chem. 276:44541-44550