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Site dsbG
- Name: dsbG
- Type: Gene
- Synonyms
b0604 MG1655 locus tag - Mnemonic: disulfide bond
- Left End Point: 13.73
- Right End Point: 13.75
- Products:
thiol-disulphide oxidase, periplasmic - Direction: <
- Priority: 0
- 3 Alleles of This Gene
dsbG601::Tn10 dsbG743(del)::kan dsbG793-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG13535 EcoliWiki dsbG - Comment:
- multicopy allows growth at lethal conc. of DTT; mutants accum.reduced, presumably misfolded, proteins in extracytoplasm, corrected by overexpr.dsbA or B or hi DTT,Cys.maintain redox bal.DsbABC syst.
- References:
- Andersen, C.L., A. Matthey-Dupraz, D. Missiakas, S. Raina 1997. A new Escherichia coli gene, dsbG, encodes a periplasmic protein involved in disulphide bond formation, required for recycling DsbA/DsbB and DsbC redox proteins. Mol.Microbiol. 26:121-132
- van Straaten, M., D. Missiakas, S. Raina, N.J. Darby 1998. The functional properties of DsbG, a thiol-disulfide oxidoreductase from the periplasm of Escherichia coli. FEBS Lett. 428:255-258
- Zheng, M., X. Wang, B. Doan, K.A. Lewis, T.D. Schneider, G. Storz 2001. Computation-directed identification of OxyR DNA binding sites in Escherichia coli. J.Bacteriol. 183:4571-4579