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Site fcl
- Name: fcl
- Type: Gene
- Synonyms
b2052 MG1655 locus tag wcaG yefB - Mnemonic: fucose, FX-like
- Left End Point: 45.79
- Right End Point: 45.81
- Products:
fucose synthetase GDP-4-keto-6-deoxy-D-mannose epimerase/reductase (bifunctional) - Direction: <
- Properties:
Property Comment encodes bifunctional protein epimerase and reductase - Priority: 0
- 1 Alleles of This Gene
fcl-750(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11788 EcoliWiki fcl - Comment:
- See fucose synthetase record: 2-step reaction.
- References:
- Stevenson, G., K. Andrianopoulos, M. Hobbs, P.R. Reeves 1996. Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid. J.Bacteriol. 178:4885-4893
- Andrianopoulos, K., L. Wang, P.R. Reeves 1998. Identification of the fucose synthetase gene in the colanic acid gene cluster of Escherichia coli K-12. J.Bacteriol. 180:998-1001
- Somers, W.S., M.L. Stahl, F.X. Sullivan 1998. GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site. Structure 6:1601-16
- Menon, S., M.L. Stahl, R. Kumar, G.Y. Xu, F.X. Sullivan 1999. Stereochemical course and steady state mechanism of the reaction catalyzed by the GDP-fucose synthetase from Escherichia coli. J.Biol.Chem. 274:26743-26750