Pay an invoice 
Site ilvH
- Name: ilvH
- Type: Gene
- Synonyms
b0078 MG1655 locus tag brnP - Mnemonic: Isoleucine-valine (requirement)
- Left End Point: 1.88
- Right End Point: 1.89
- Products:
AHAS III, valine-sensitive, small subunit acetolactate synthase III, valine-sensitive, ALS III - Direction: >
- Priority: 1
- 4 Alleles of This Gene
ilvH611 ilvH612 ilvH613 ilvH785(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank M10738 NCBI/GenBank X01609 EcoGene.org EG10499 EcoliWiki ilvH - Comment:
- Selectable phenotype. Increased expression: a-aminobutyrate resistance; valine resistance; glycylleucine, phenylalanylleucine resistance. Valine resistance.
- References:
- Ramakrishnan, T., E.A. Adelberg 1965. Regulatory mechanisms in the biosynthesis of isoleucine and valine. II. Identification of two operator genes. J.Bacteriol. 89:654-660
- Umbarger, H.E. 1969. Regulation of the biosynthesis of the branched-chain amino acids. Curr.Topics Microbiol.Immunol. 1:57-76
- Davis, E.J., J.M. Blatt, E.K. Henderson, J.J. Whittaker, J.H. Jackson 1977. Valine-sensitive acetohydroxy acid synthetases in Escherichia coli K-12: unique regulation modulated by multiple genetic sites. Mol.Gen.Genet. 156:239-249
- LaCara, F., M. DeFelice 1979. Chromatographic detection of the acetohydroxy acid synthetase isoenzymes of Escherichia coli K-12. Biochem.Biophys.Res.Commun. 91:319-326
- Sutton, A., T. Newman, M. Francis, M. Freundlich 1981. Valine-resistant Escherichia coli K-12 strains with mutations in the ilvB operon. J.Bacteriol. 148:998-1001
- Squires, C., M. DeFelice, S.R. Wessler, J.M. Calvo 1981. Physical characterization of the ilvH1 operon of Escherichia coli K-12. J.Bacteriol. 147:797-804
- Gollop, N., H. Tavori, Z. Barak 1982. Acetohydroxy acid synthase is a target for leucine-containing peptide toxicity in Escherichia coli. J.Bacteriol. 149:387-390
- Squires, C.H., M. DeFelice, J. Devereux, J.M. Calvo 1983. Molecular structure of ilvIH and its evolutionary relationship to ilvG in Escherichia coli K-12. Nucleic Acids Res. 11:5299-5313
- Jans, D.A., A.L. Fimmel, L. Langman, L.B. James, J.A. Downie, A.E. Senior, G.R. Ash, F. Gibson, G.B. Cox 1983. Mutations in the uncE gene affecting assembly of the c-subunit of the adenosine triphosphatase of Escherichia coli. Biochem.J. 211:717-726
- Platko, J.V., D.A. Willins, J.M. Calvo 1990. The ilvIH operon of Escherichia coli is positively regulated. J.Bacteriol. 172:4563-4570
- Baccigalupi, L., R. Marasco, E. Ricca, M. De Felice, M. Sacco 1995. Control of ilvIH transcription during amino acid downshift in stringent and relaxed strains of Escherichia coli. FEMS Microbiol.Lett. 131:95-100