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Site hpt
- Name: hpt
- Type: Gene
- Synonyms
b0125 MG1655 locus tag - Mnemonic: HGPRT
- Left End Point: 3.05
- Right End Point: 3.06
- Products:
hypoxanthine-guanine phosphoribosyltransferase guanine phosphoribosyl transferase IMP phophoribosidase HGPRTase - Direction: >
- Priority: 1
- 2 Alleles of This Gene
hpt-1 hpt-743(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG20098 EcoliWiki hpt - Comment:
- Selectable phenotype. Loss: hypoxanthine + sulfanilamide resistance. In gpt-: 6-mercaptopurine resistance.
- References:
- Jochimsen, B., P. Nygaard, T. Vestergaard 1975. Location on the chromosome of Escherichia coli of genes governing purine metabolism. Adenosine deaminase (add), guanosine kinase (gsk) and hypoxanthine phosphoribosyltransferase (hpt). Mol.Gen.Genet. 143
- Bruce, I., J. Hardy, K.A. Stacey 1984. Potentiation by purines of the growth-inhibitory effects of sulphonamides on Escherichia coli K-12 and the location of the gene which mediates this effect. J.Gen.Microbiol. 130:2489-2495