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Site rseP
- Name: rseP
- Type: Gene
- Synonyms
b0176 MG1655 locus tag ecf Darigalongue et al. for E sigma factor regulation yaeL - Mnemonic: regulation of sigma E
- Left End Point: 4.24
- Right End Point: 4.27
- Products:
inner membrane zinc metalloprotease - Direction: >
- Properties:
Property Comment essential gene rpoE regulon - Priority: 0
- External Database Links:
Host Site Page Links EcoGene.org EG12436 EcoliWiki rseP - Comment:
- Multicopy rpoE suppresses ecfE mutant. RseP(YaeL) cleaves RseA at cytoplasmic or intramembrane site following RseA cleavage by DegS at periplasmic site.
- References:
- Dartigalongue, C., H. Loferer, S. Raina 2001. EcfE, a new essential inner membrane protease: its role in the regulation of heat shock response in Escherichia coli. EMBO J. 20:5908-5918
- Drew, D., D. Sjostrand, J. Nilsson, T. Urbig, C.N. Chin, J.W. de Gier, G. von Heijne 2002. Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis. Proc.Natl.Acad.Sci.USA 99:2690-2695
- Akiyama, Y., K. Kanehara, K. Ito 2004. RseP (YaeL), an Escherichia coli RIP protease, cleaves transmembrane sequences. EMBO J 23:4434-4442
- Grigorova, I.L., R. Chaba, H.J. Zhong, B.M. Alba, V. Rhodius, C. Herman, C.A. Gross 2004. Fine-tuning of the Escherichia coli sigmaE envelope stress response relies on multiple mechanisms to inhibit signal-independent proteolysis of the transmembrane a