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Site - wzxESite wzxE Site wzxE
- Name: wzxE
- Type: Gene
- Synonyms
|
b3792 | MG1655 locus tag |
wzx | |
- Mnemonic: Temporary systematic nomenclature
- Left End Point: 85.66
- Right End Point: 85.69
- Direction: >
- Properties:
Property | Comment |
---|
encodes membrane protein | translocates O-antigen subunits |
- Priority: 0
- External Database Links:
- Comment:
- Null mutants accumulate lipid III and die, unless also rfe- (wecA-), making them unable to synthesize lipid III. Putative transporter Wzx flips O-antigen from inner to outer surface of IM.
- References:
- Rick, P.D., K. Barr, K. Sankaran, J. Kajimura, J.S. Rush, C.J. Waechter 2003. Evidence that the wzxE gene of Escherichia coli K-12 encodes a protein involved in the transbilayer movement of a trisaccharide-lipid intermediate in the assembly of enteroba
- Raetz, C.R., C.M. Reynolds, M.S. Trent, R.E. Bishop 2007. Lipid A modification systems in gram-negative bacteria. Annu.Rev.Biochem. 76:295-329