Site arcA
- Name: arcA
- Type: Gene
- Synonyms
b4401 MG1655 locus tag dye fexA msp male-specific phage seg sfrA - Mnemonic: Aerobic pathways control
- Left End Point: 99.96
- Right End Point: 99.97
- Products:
regulatory component of 2-component ArcBA sensor-regulator system - Direction: <
- Priority: 1
- 4 Alleles of This Gene
arcA43(del) arcA44(del)::kan arcA45(del) arcA726(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10061 EcoliWiki arcA - Comment:
- negative regulatory gene of genes in aerobic pathways. anaerobic repression. 'dye' synonym = sens. to redox dyes, toluidine blue. Prod. has helix-turn-helix motif.also activates cydAB operon
- References:
- Beutin, L., P.A. Manning, M. Achtman, N. Willets 1981. sfrA and sfrB products of Escherichia coli K-12 are transcriptional control factors. J.Bacteriol. 145:840-844
- Buxton, R.S., L.S. Drury 1983. Cloning and insertional inactivation of the dye (sfrA) gene, mutation of which affects sex factor F expression and dye sensitivity of Escherichia coli K-12. J.Bacteriol. 154:1309-1314
- Buxton, R.S., L.S. Drury 1984. Identification of the dye gene product, mutational loss of which alters envelope protein composition and also affects sex factor F expression in Escherichia coli. Mol.Gen.Genet. 194:241-247
- Drury, L.S., R.S. Buxton 1985. DNA sequence analysis of the dye gene of Escherichia coli reveals amino acid homology between the Dye and OmpR proteins. J.Biol.Chem. 260:4236-4242
- Iuchi, S., E.C.C. Lin 1988. arcA (dye), a global regulatory gene in Escherichia coli mediating repression of enzymes in aerobic pathways. Proc.Natl.Acad.Sci.USA 85:1888-1892
- Silverman, P.M., S. Rother, H. Gaudin 1991. Arc and Sfr functions of the Escherichia coli K-12 arcA gene product are genetically and physiologically separable. J.Bacteriol. 173:5648-52
- Chattopadhyay, S., Y. Wu, P. Datta 1997. Involvement of Fnr and ArcA in anaerobic expression of the tdc operon of Escherichia coli. J.Bacteriol. 179:4868-4873
- Strohmaier, H., R. Noiges, S. Kotschan, G. Sawers, G. Hogenauer, E.L. Zechner, G. Koraimann 1998. Signal transduction and bacterial conjugation: characterization of the role of ArcA in regulating conjugative transfer of the resistance plasmid R1. J.Mol