Site thrS
- Name: thrS
- Type: Gene
- Synonyms
b1719 MG1655 locus tag - Mnemonic: threonine
- Left End Point: 38.77
- Right End Point: 38.81
- Products:
threonyl-tRNA synthetase - Direction: <
- Properties:
Property Comment autogenously regulated NULL - Priority: 1
- 2 Alleles of This Gene
thrS1029 thrS791-YFP(::cat) - External Database Links:
Host Site Page Links EcoGene.org EG11001 EcoliWiki thrS - Comment:
- Selectable phenotype. Borrelidin resistance.
- References:
- Paetz, W., G. Nass 1973. Biochemical and immunological characterization of threonyl-tRNA synthetase of two borrelidin-resistant mutants of Escherichia coli K-12. Eur.J.Biochem. 35:331-337
- Nass, G., J. Thomale 1974. Alteration of structure or level of threonyl-tRNA synthetase in borrelidin-resistant mutants of Escherichia coli. FEBS Lett. 39:182-186
- Plumbridge, J.A., M. Springer, M. Graffe, R. Goursot, M. Grunberg-Manago 1980. Physical localisation and cloning of the structural gene for E. coli initiation factor IF3 from a group of genes concerned with translation. Gene 11:33-42
- Frohler, J., A. Rechenmacher, J. Thomale, G. Nass, A. Bock 1980. Genetic analysis of mutations causing borrelidin resistance by overproduction of threonyl-transfer ribonucleic acid synthetase. J.Bacteriol. 143:1135-1141
- Springer, M., J.A. Plumbridge, M. Trudel, M. Graffe, M. Grunberg-Manago 1982. Transcription units around the gene for E. coli translation initiation factor IF3 (infC). Mol.Gen.Genet. 186:247-252
- Plumbridge, J.A., M. Springer 1982. Escherichia coli phenylalanyl-tRNA synthetase operon: transcription studies of wild-type mutated operons on multicopy plasmids. J.Bacteriol. 152:661-668
- Mayaux, J.-F., G. Fayat, M. Fromant, M. Springer, M. Grunberg-Manago 1983. Structural and transcriptional evidence for related thrS and infC expression. Proc.Natl.Acad.Sci.USA 80:6152-6156
- Wu, T.-H., D.L. Wood, P.L. Stein, M.M. Comer 1984. Transcription of a gene cluster coding for two aminoacyl-tRNA synthetases and an initiation factor in Escherichia coli. J.Mol.Biol. 173:177-209
- Springer, M., M. Graffe, J.S. Butler, M. Grunberg-Manago 1986. Genetic definition of the translational operator of the threonine-tRNA ligase gene in Escherichia coli. Proc.Natl.Acad.Sci.USA 83:4384-4388
- Pramanik, A., S.J. Wertheimer, J.J. Schwartz, I. Schwartz 1986. Expression of Escherichia coli infC: identification of a promoter in an upstream thrS coding sequence. J.Bacteriol. 168:746-751
- Wertheimer, S.J., R.A. Klotsky, I. Schwartz 1988. Transcriptional patterns for the thrS-infC-rpLT operon of Escherichia coli. Gene 63:309-320
- Maloy, S.R., V.J. Stewart 1993. Autogenous regulation of gene expression. J.Bacteriol. 175:307-316
- Nogueira, T., M. de Smit, M. Graffe, M. Springer 2001. The relationship between translational control and mRNA degradation for the Escherichia coli threonyl-tRNA synthetase gene. J.Mol.Biol. 310:709-722
- Torres-Larios, A., A.C. Dock-Bregeon, P. Romby, B. Rees, R. Sankaranarayanan, J. Caillet, M. Springer, C. Ehresmann, B. Ehresmann, D. Moras 2002. Structural basis of translational control by Escherichia coli threonyl tRNA synthetase. Nat.Struct.Biol. 9