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Site ffs
- Name: ffs
- Type: Gene
- Synonyms
b0455 MG1655 locus tag - Mnemonic: four.five s
- Left End Point: 10.24
- Right End Point: 10.25
- Products:
4.5S rRNA - Direction: >
- Priority: 1
- External Database Links:
Host Site Page Links NCBI/GenBank X01074 EcoGene.org EG30027 EcoliWiki ffs - Comment:
- part of ribonucleoprotein particle similar to mammalian signal recognition particle. Both the Ffs and the Ffh are homologous to SRP counterparts. cotranslational integration of proteins into membrane.
- References:
- Brown, S., M.J. Fournier 1984. The 4.5S RNA gene of Escherichia coli is essential for cell growth. J.Mol.Biol. 178:533-550
- Hsu, L.M., J. Zagorski, M.J. Fournier 1984. Cloning and sequence analysis of the Escherichia coli 4.5S RNA gene. J.Mol.Biol. 178:509-531
- Macfarlane, J., M. Muller 1995. The functional integration of a polytopic membrane protein of Escherichia coli is dependent on the bacterial signal-recognition particle. Eur.J.Biochem. 233:766-771
- Dong, H., L.A. Kirsebom, L. Nilsson 1996. Growth rate regulation of 4.5 S RNA and M1 RNA the catalytic subunit. J.Mol.Biol. 261:303-308
- Batey, R.T., M.B. Sagar, J.A. Doudna 2001. Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle. J.Mol.Biol. 307:229-246
- Park, S.K., F. Jiang, R.E. Dalbey, G.J. Phillips 2002. Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant. J.Bacteriol. 184:2642-2653
- Tian, H., J. Beckwith 2002. Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway. J.Bacteriol. 184:111-118