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Site uvrC
- Name: uvrC
- Type: Gene
- Synonyms
b1913 MG1655 locus tag - Mnemonic: Ultraviolet repair
- Left End Point: 42.91
- Right End Point: 42.95
- Products:
excision nuclease - Direction: <
- Priority: 1
- 6 Alleles of This Gene
uvrC152 uvrC279::Tn10 uvrC33 uvrC34 uvrC759(del)::kan uvrC793-YFP(::cat) - External Database Links:
Host Site Page Links NCBI/GenBank X03691 EcoGene.org EG11063 EcoliWiki uvrC - Comment:
- diploid {\it uvrC} gives mucoidy (F500).
- References:
- Novel, M., G. Novel 1976. Regulation of beta-glucuronidase synthesis in Escherichia coli K-12: constitutive mutants specifically derepressed for uidA expression. J.Bacteriol. 127:406-417
- Yoakum, G.H., L. Grossman 1981. Identification of E. coli uvrC protein. Nature 292:171-173
- Sharma, S., A. Ohta, W. Dowhan, R.E. Moses 1981. Cloning of the uvrC gene of Escherichia coli: expression of a DNA repair gene. Proc.Natl.Acad.Sci.USA 78:6033-6037
- Sancar, A., B.M. Kacinski, D.L. Mott, W.D. Rupp 1981. Identification of the uvrC gene product. Proc.Natl.Acad.Sci.USA 78:5450-5454
- Sharma, R.C., W. Dowhan, R.E. Moses 1982. Molecular structure of the uvrC gene of Escherichia coli: identification of DNA sequences required for transcription of the uvrC gene. Nucleic Acids Res. 10:5209-5221
- Tucker, S.D., A.S. Gopalakrishnan, R. Bollinger, W. Dowhan, E. Murgola 1982. Molecular mapping of glyW, a duplicate gene for tRNA_3^Gly of Escherichia coli. J.Bacteriol. 152:773-779
- Sancar, A., W.D. Rupp 1983. A novel repair enzyme UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region. Cell 33:249-260
- Van Sluis, C.A., G.F. Moolenaar, C. Backendorf 1983. Regulation of the uvrC gene of Escherichia coli K12: localization and characterization of a damage-inducible promoter. EMBO J. 2:2313-2318
- Sancar, G.B., A. Sancar, W.D. Rupp 1984. Sequences of the urrC gene and protein. Nucleic Acids Res. 12:4593-4608
- Forster, J.W., P. Strike 1985. Organization and control of the Escherichia coli uvrC gene. Gene 35:71-82
- Sharma, S., T.F. Stark, W.G. Beattie, R.E. Moses 1986. Multiple control elements for the uvrC gene unit of Escherichia coli. Nucleic Acids Res. 14:2301-2318
- Moolenaar, G.F., C.A. Van Sluis, C. Backendorf, P. Van de Putte 1987. Regulation of the Escherichia coli excision repair gene uvrC. Overlap between the uvrC structural gene and the region coding for a 24 kD protein. Nucleic Acids Res. 15:4273-4289
- Forster, J.W., P. Strike 1988. Analysis of the regulatory elements of the Escherichia coli uvrC gene by construction of operon fusions. Mol.Gen.Genet. 211:531-537
- Tomer, G., O. Cohen-Fix, M.A. O'Donnell, M. Goodman, Z. Livneh 1996. Reconstitution of repair-gap UV mutagenesis with purified proteins from Escherichia coli: a role for DNA polymerases III and II. Proc.Natl.Acad.Sci.USA 93:1376-1380
- Sancar, A. 1996. DNA excision repair. Annu.Rev.Biochem. 65:43-81