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Site galK
- Name: galK
- Type: Gene
- Synonyms
b0757 MG1655 locus tag - Mnemonic: Galactose
- Left End Point: 16.99
- Right End Point: 17.01
- Products:
galactokinase - Direction: <
- Priority: 1
- 13 Alleles of This Gene
galK0 galK16 galK2(Oc) galK24 galK30 galK35 galK42(Am) galK48 galK539(del)::lacZp-tetR-mCerulean,kan galK62 galK729(del)::kan galK8 galK900 - External Database Links:
Host Site Page Links EcoGene.org EG10363 EcoliWiki galK - Comment:
- Selectable phenotype. Loss: 2-deoxygalactose resistance, In galE: galactose resistance. In galT: galactose resistance; in galU-: galactose resistance. Loss: 2-deoxygalactose resistance. Strains deficient in galK are unable to ferment galactose.
- References:
- Yarmolinsky, M., H. Wiesmeyer, H.M. Kalckar, E. Jordan 1959. Hereditary defects in galactose metabolism in Escherichia coli mutants. II. Galactose-induced sensitivity. Proc.Natl.Acad.Sci.USA 45:1786-1791
- Lederberg, E.M. 1960. Genetic and functional aspects of galactose metabolism in E. coli. Symp.Soc.Gen.Microbiol. 10:115-131
- Sundararajan, T.A. 1963. Interference with glycerokinase induction in mutants of E. coli accumulating gal-1-P. Proc.Natl.Acad.Sci.USA 50:463-469
- Saedler, H., A. Gullon, P. Starlinger 1968. Negative control of the galactose operon in E. coli. Mol.Gen.Genet. 102:79-88
- Barak, Z., C. Gilvarg 1974. Triornithine-resistant strains of Escherichia coli. Isolation, definition, and genetic studies. J.Biol.Chem. 249:143-148
- Debouck, C., A. Riccio, D. Schumperli, K. McKenney, J. Jeffers, C. Hughes, M. Rosenberg, M. Heusterspreute, J. Davison 1985. Structure of the galactokinase gene of Escherichia coli, the last (?) gene of the gal operon. Nucleic Acids Res. 13:1841-1853
- Weichert, M.J., S. Adhya 1993. The galactose regulon of Escherichia coli. Mol.Microbiol. 10:245-251