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Site eda
- Name: eda
- Type: Gene
- Synonyms
b1850 MG1655 locus tag hga observation in post-SOS recovery kdgA kga - Mnemonic: Entner-Douderoff aldolase
- Left End Point: 41.61
- Right End Point: 41.62
- Products:
2-keto-3-deoxygluconate 6-phosphate aldolase 2-keto-4-hydroxyglutarate aldolase - Direction: <
- Priority: 1
- 6 Alleles of This Gene
eda-1 eda-10 eda-3126::Tn10kan eda-50 eda-51::Tn10 eda-775(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10256 EcoliWiki eda - Comment:
- Get apparent reversions (growth on gluconate) but are mutations in a 2nd gene. Prevents accum. of KdgP, which inhibits growth of eda- strain. Second Mut. is edd.Select on glucuronate, not gluconate.
- References:
- Fradkin, J.E., D. Fraenkel 1971. 2-keto-3-deoxygluconate 6-phosphate aldolase mutants of Escherichia coli. J.Bacteriol. 108:1277-1283
- Fraenkel, D., S. Banerjee 1972. Deletion mapping of zwf, the gene for a constitutive enzyme, glucose 6-phosphate dehydrogenase in Escherichia coli. Genetics 71:481-489
- Vlahos, C.J., E.E. Dekker 1988. The complete amino acid sequence and identification of the active-site arginine peptide of Escherichia coli 2-keto-4-hydroxyglutarate aldolase. J.Biol.Chem. 263:11683-11691
- Conway, T., K.C. Yi, S.E. Egan, R.E. Wolf, D.L. Rowley 1991. Locations of the zwf, edd and eda genes on the Escherichia coli physical map. J.Bacteriol. 173:5247-5248
- Carter, A.T., B.M. Pearson, J.R. Dickinson, W.E. Lancashire 1993. Sequence of the Escherichia coli K-12 edd and eda genes of the Entner-Douderoff pathway. Gene 130:155-156